Pesquisa sobre:
CYCLIN-DEPENDENT KINASE INHIBITOR P27
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DeCS
Descritor
Inglês
:
Cyclin-Dependent Kinase Inhibitor p27
Descritor
Espanhol
:
Inhibidor p27 de las Quinasas Dependientes de la Ciclina
Descritor
Português
:
Inibidor de Quinase Dependente de Ciclina p27
Categoria:
D12.644.360.225.600
D12.776.167.187.600
D12.776.476.225.600
D12.776.624.776.355.600
Definição
Inglês
:
A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and
CYCLIN-DEPENDENT KINASES
during the
CELL CYCLE
. It interacts with active
CYCLIN D
complexed to
CYCLIN-DEPENDENT KINASE 4
in proliferating cells, while in arrested cells it binds and inhibits
CYCLIN E
complexed to
CYCLIN-DEPENDENT KINASE 2.
Ação Farmacológica:
Protein Kinase Inhibitors
Nota Histórica
Inglês
:
2006(1992)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50932
Identificador Único:
D050760
Ocorrência na BVS
:
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